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| Sunless Skies | Fallen London | Windows, macOS, Linux, PlayStation 4, Xbox One, Nintendo Switch | England | 2019 |
| Super Castlevania IV | Castlevania | Super Nintendo | Japan | 1991 |
| Super Ghouls ’n Ghosts | Ghosts ’n Goblins | Super Nintendo, Game Boy Advance | Japan | 1991 |
| Super Lone SurvivorRM | Lone Survivor | Windows, Nintendo Switch | England | 2022 |
| Super Metroid | Metroid | Super Nintendo | Japan | 1994 |
| Super Punch-Out!! | Punch-Out!! | Super Nintendo | Japan | 1994 |
| Super Punch-Out!! | Punch-Out!! | Arcade | Japan | 1984 |
| Super Street Fighter II | Street Fighter | Arcade, Super Nintendo, Sega Genesis, X68000, FM Towns, Amiga, MS-DOS | Japan | 1993 |
| Super Street Fighter II Turbo | Street Fighter | Arcade, 3DO Interactive Multiplayer, MS-DOS, Amiga, Dreamcast | Japan | 1994 |
| Super Street Fighter II Turbo HD RemixRS | Street Fighter | PlayStation 3, Xbox 360 | Vereinigte Staaten | 2008 |
| SWAT 3: Close Quarters Battle | SWAT | Windows | Vereinigte Staaten | 1999 |
| SWAT 4: Special Weapons and Tactics | SWAT | Windows | Vereinigte Staaten | 2005 |
| Sword of Mana | Mana | Game Boy Advance | Japan | 2003 |
| Syndicate | Syndicate | England | 1993 | |
| SyndicateRB | Syndicate | Windows, PlayStation 3, Xbox 360 | Schweden | 2012 |
| Syndicate Wars | Syndicate | MS-DOS, PlayStation | England | 1996 |
| Syphon Filter | Syphon Filter | PlayStation | Vereinigte Staaten | 1999 |
| Syphon Filter 2 | Syphon Filter | PlayStation | Vereinigte Staaten | 2000 |
| Syphon Filter 3 | Syphon Filter | PlayStation | Vereinigte Staaten | 2001 |
| Syphon Filter: Combat Ops | Syphon Filter | Vereinigte Staaten | 2007 | |
| Syphon Filter: Dark Mirror | Syphon Filter | PlayStation Portable, PlayStation 2 | Vereinigte Staaten | 2006 |
| Syphon Filter: Logan’s Shadow | Syphon Filter | PlayStation Portable, PlayStation 2 | Vereinigte Staaten | 2007 |
| Syphon Filter: The Omega Strain | Syphon Filter | PlayStation 2 | Vereinigte Staaten | 2004 |
| System Shock | System Shock | Vereinigte Staaten | 1994 | |
| System Shock 2 | System Shock | Vereinigte Staaten | 1999 | |
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